![]() ![]() MEGGLE offers a variety of PS/PSD of milled lactose grades offering flexibility in tableting during the second compaction step.Įxtrusion/spheronization processes also make use of milled lactose as a filler.Īfter all, disaccharide lactose may be metabolized by bacteria or fungi and is mainly used in its milled form as bulk substrate/medium for fermentation in bio-industries. In well-established slugging processes flat compacts are manufactured preferentially avoiding die filling issues. In roller compaction due to force feeding reduced powder flow is of minor importance, in some cases low segregation tendency of milled lactose grades may be even seen advantageous for content uniformity reasons. These processes consist of a primary agglomeration and a final milling step. Milled lactose grades also have a long tradition in dry granulation procedures using roller compaction or slugging. Dispersion of a milled lactose suspension through a nozzle allows to optimize particle porosity, shape and surface in one step, resulting into the product group of spray-dried lactose (FlowLac ® 90/100). Date HS Code Description Origin Country Port of Discharge Unit Quantity Value (INR) Per Unit (INR) Nov 22 2016: 17021190: MICROCELAC 100 (LACTOSE MONOHYDRATE PH.EUR. Impacting particle characteristics by agglomeration has been an early undertaking, where flowability was optimized by a simple and gentle particle size enlargement step, leading into the product family of agglomerated Tablettose ®. Milled lactose grades represent a perfect product platform, for they can be modified greatly, fulfilling the needs of various applications. ![]() in economical direct compression) both compactibility and flowability are primordial. ![]() However, for many important pharmaceutical agglomeration processes (e.g. Brittle α-lactose monohydrate exhibits good binding properties, and consolidates mainly by fragmentation, but particle flow of milled lactose grades is moderate, depending on size and its corresponding specific surface Milled lactose grades: A perfect product platform This allows to modulate in particular a solid formulation’s compactibility, compressibility, porosity, and segregation tendency. Milled α-lactose monohydrate is available in fine particle size (PS) with narrow particle size distribution (PSD), defined surface properties and density ranges. In traditional, pharmaceutical dry and wet granulation operation finer particles have proven to be beneficial. The right milled lactose product for wet and dry granulation ![]()
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